Related Experiment Video
Updated: Mar 9, 2026

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
Published on: May 21, 2019
Standing shock index: An alternative to orthostatic vital signs
1Department of Emergency Medicine, University of Maryland School of Medicine, 110S. Paca St., 6th Floor, Suite 200, Baltimore, MD 21201, United States.
Abstract:
Objective The lack of a sensitive, practical bedside test for hypovolemia has rekindled interest in the shock index (heart rate divided by systolic blood pressure). Here, we compare the effect of blood donation on standing shock index values with its effect on values for the supine shock index and orthostatic change in shock indicies (OCSI).
Methods:
This is a re-analysis of data collected for an earlier report. Data were available from 292 adults below age 65 and 44 adults ages 65 and over, donating 450mL of blood. We obtained supine and standing vital signs before and after donation and then calculated 95% confidence intervals for differences based on the t-distribution.
Results:
Blood donation resulted in a mean increase in the standing shock index of 0.09 [95% CI, 0.08-0.11] in younger adults and 0.08 [95% CI, 0.05-0.11] in older adults. These changes were similar to those noted for OCSI (young, 95% CI, 0.08-0.10; old, 95% CI, 0.04-0.10). Supine shock index values did not change with donation in younger donors (mean difference 0.0 [95% CI, 0.0-0.01]) or older donors (mean difference 0.0 [95% CI, -0.01-0.03]).
Conclusion:
Blood donation does not affect the supine shock index, but it does result in changes in standing shock index that are similar to changes in more complicated orthostatic vital signs.
Related Concept Videos
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Uniform Distribution
Two essential properties of this distribution are
Shock Waves
When the source's speed approaches the speed of sound, constructive interference between successive wavefronts emitted by the source occurs immediately behind it. Initially, scientists believed that this constructive interference would result in such high...
z Scores and Unusual Values
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
Standard Deviation
Calculating Standard Deviation
The standard deviation value is small when all the data is concentrated close to the mean. Here the data exhibits low variation. The standard deviation value is larger when the data values are more spread out from the mean. Here, the data displays high...

