Related Experiment Video
Updated: Mar 9, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Mood disorders in first- and second-generation immigrants: systematic review and meta-analysis
Irina Mindlis1, Paolo Boffetta2
1Irina Mindlis, MPH, Lic, Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, USA; Paolo Boffetta, MD, MPH, Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, USA Irina.mindlis@mssm.edu.
None:
BackgroundAlthough there are consistent reports of higher psychosis rates among immigrants, the information on mood disorders is limited.AimsTo review and quantify the difference in incidence of mood disorders in first- and second-generation immigrant (FGI and SGI) groups v. non-immigrants.MethodPubMed, EMBASE and PsycINFO were searched for articles from cohort studies reporting incidence of mood disorders among FGIs and SGIs.ResultsEighteen studies met our inclusion criteria. The summary relative risk (RR) for FGIs was 1.25 (95% CI 1.11-1.41), based on 17 effect sizes and 6120 cases, and 1.16 (95% CI 0.96-1.40) for SGIs based on three effect sizes. Men seemed at higher risk (RR = 1.29, 95% CI 1.06-1.56).ConclusionsClinicians should view FGIs as a group at risk of mood disorders, especially men. Further research is needed to understand immigrants' risk, especially in SGI.
Related Concept Videos
Psychological and Sociocultural Causes of Schizophrenia
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Surveys
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Ethnic Identity within a Larger Culture
Diagnostic and Statistical Manual of Mental Disorders (DSM)

