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DNA sequence properties that predict susceptibility to epiallelic switching.

Marco Catoni1,2, Jayne Griffiths1, Claude Becker3

  • 1The Sainsbury Laboratory, University of Cambridge, Cambridge, UK.

The EMBO Journal
|January 11, 2017
PubMed
Summary

DNA methylation patterns, crucial for epigenetic inheritance, were studied in Arabidopsis MET1 mutants. DNA sequence features like CpG density and repetitiveness influence epiallelic switching, impacting transgenerational inheritance.

Keywords:
DNA methylationepiallelesepigenetictranscriptional silencing

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