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Campylobacter pylori infection in Meckel's diverticula containing gastric mucosa

A Morris1, G Nicholson, J Zwi

  • 1Department of Microbiology, Auckland Hospital, New Zealand.

Gut
|September 1, 1989
PubMed

Insights

Campylobacter pylori, now known as Helicobacter pylori, was found in a Meckel

Area of Science:

  • Gastroenterology
  • Microbiology
  • Surgical Pathology

Background:

  • Meckel's diverticula are congenital anomalies that can contain ectopic gastric mucosa.
  • Helicobacter pylori is a bacterium primarily associated with gastroduodenal diseases.

Observation:

  • A retrospective analysis of 228 resected Meckel's diverticula was performed.
  • Gastric mucosa was identified in 65 of the resected diverticula.

Findings:

  • One Meckel's diverticulum with gastric mucosa showed heavy infection with organisms morphologically consistent with H. pylori.
  • The infection and inflammation were confined to the ectopic gastric mucosa within the diverticulum.
  • The patient was a 6-year-old boy presenting with small bowel obstruction.

Implications:

  • This finding suggests that H. pylori can infect gastric mucosa outside the typical gastroduodenal region.
  • The presence of H. pylori in Meckel's diverticula may indicate an orofaecal transmission route.
  • Further research is needed to understand the clinical significance and prevalence of H. pylori in ectopic gastric tissues.

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