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Updated: Mar 9, 2026

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[A case report for primary yolk sac tumor of endometrium]
1Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Abstract:
A case of primary yolk sac tumor of endometrium was retrospectively analyzed and relevant literature was systematically reviewed. We found that the primary yolk sac tumor of endometrium showed low incidence rate and was clinically characterized by abnormal vaginal bleeding, intrauterine lesions and significantly elevated alpha-fetoprotein (AFP) level. The final diagnosis should be confirmed by pathological examination. There is no guideline for the treatment of primary yolk sac tumor of endometrium due to its rareness. For now, surgery and chemotherapy are the major therapies and the curative effect is satisfactory in some cases.
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