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Updated: Mar 9, 2026

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Solvent-Free Strategy Yields Size and Shape-Uniform Capsules.

Ana M S Costa1, João F Mano1

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Summary

Superamphiphobic surfaces enable precise fabrication of liquefied-core capsules. This novel method offers high efficiency and versatility for creating advanced materials for various applications.

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Area of Science:

  • Materials Science and Engineering
  • Polymer Chemistry
  • Surface Science

Background:

  • Polymeric capsules are widely used in diverse fields, including biomedical applications, cosmetics, agriculture, and electronics.
  • Existing strategies for capsule fabrication often lack precise control over particle characteristics or require harsh processing conditions.
  • The development of novel methods for fabricating advanced polymeric capsules with tailored properties is crucial for next-generation materials.

Purpose of the Study:

  • To develop a new strategy for fabricating capsules with a liquefied core using superamphiphobic surfaces.
  • To demonstrate the advantages of this method, including precise control over size and shape, high encapsulation efficiency, and mild processing conditions.
  • To showcase the versatility of the method by encapsulating various liquid cores within polymeric shells.

Main Methods:

  • Fabrication of capsules via the assembly of polymeric droplets induced by superamphiphobic surfaces.
  • Utilizing a photo-cross-linkable derivative of chitosan for the polymeric shell.
  • Employing reversible cross-linking, interfacial gelation, or ice as template cores for various liquid core materials.

Main Results:

  • Superamphiphobic surfaces allowed for easy and precise control over the size and shape of the fabricated capsules.
  • The developed method achieved high encapsulation efficiency for the liquefied cores.
  • Mild processing conditions were maintained, and a variety of water or oil-based liquid cores were successfully encapsulated.

Conclusions:

  • The developed superamphiphobic surface-induced strategy provides a versatile and efficient method for fabricating liquefied-core polymeric capsules.
  • This approach overcomes limitations of current strategies, offering precise control and mild conditions.
  • The technology holds significant potential for advancing materials in biomedical, cosmetic, agricultural, and electronic applications.