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Factors affecting the course of body and kidney growth in infants with urolithiasis: A critical long-term evaluation
Kemal Sarica1, Fatma Narter, Kubilay Sabuncu
1Dr. Lutfi Kirdar Training and Research Hospital Urology Clinic, Istanbul. saricakemal@gmail.com.
Insights
Longer breastfeeding and fewer urinary tract infections (UTIs) and stone attacks promote better growth in infants with kidney stones. Close monitoring can prevent growth issues in these children.
Area of Science:
- Pediatric Nephrology
- Growth and Development
- Urinary Tract Disorders
Background:
- Infant kidney stone disease can impact long-term health and growth.
- Identifying factors influencing clinical course and growth is crucial for management.
Purpose of the Study:
- To investigate dietary, patient, and stone-related factors affecting infant kidney stone disease.
- To assess the impact of these factors on body and renal growth.
Main Methods:
- A cohort of 50 infants with a history of stone disease was studied.
- Factors evaluated included anatomical abnormalities, urinary tract infections (UTIs), comorbidities, stone characteristics, and feeding practices (breastfeeding duration, formula use).
- Long-term follow-up assessed effects on body and renal growth.
Main Results:
- Infants with longer exclusive breastfeeding showed better growth percentiles.
- Higher frequency of UTIs and stone attacks significantly impacted growth negatively.
- Close follow-up and interventions can mitigate growth retardation and renal problems.
Conclusions:
- Breastfeeding duration, UTI frequency, stone recurrence, and interventions are key factors in infant kidney stone disease.
- These factors significantly influence long-term body and kidney growth.
- Proactive management is essential to prevent growth complications.
Objective:
To investigate the possible effects of dietary, patient and stone related factors on the clinical course of the stone disease as well as the body and renal growth status of the infants.
Patients And Methods:
A total of 50 children with an history of stone disease during infancy period were studied. Patient (anatomical abnormalities, urinary tract infection - UTI, associated morbidities), stone (obstruction, UTI and required interventions) and lastly dietary (duration of sole breast feeding, formula feeding) related factors which may affect the clinical course of the disease were all evaluated for their effects on the body and renal growth during long-term follow-up.
Results:
Mean age of the children was 2.40 ± 2.65 years. Our findings demonstrated that infants receiving longer period of breast feeding without formula addition seemed to have a higher rate of normal growth percentile values when compared with the other children. Again, higher frequency of UTI and stone attacks affected the growth status of the infants in a remarkable manner than the other cases. Our findings also demonstrated that thorough a close follow-up and appropriately taken measures; the possible growth retardation as well as renal growth problems could be avoided in children beginning to suffer from stone disease during infancy period.
Conclusions:
Duration of breast feeding, frequency of UTI, number of stone attacks and stone removal procedures are crucial factors for the clinical course of stone disease in infants that may affect the body as well as kidney growth during long-term follow-up.
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