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Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Mar 9, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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MRI/US fusion prostate biopsy: Our initial experience.

Vito Lacetera1, Bernardo Cervelli, Antonio Cicetti

  • 1Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro. Vito.Lacetera@gmail.com.

Archivio Italiano Di Urologia, Andrologia : Organo Ufficiale [Di] Societa Italiana Di Ecografia Urologica E Nefrologica
|January 12, 2017
PubMed
Summary

Magnetic resonance imaging/ultrasound (MRI/US) fusion biopsy shows promise for prostate cancer detection. This initial experience with 59 patients demonstrated effective risk stratification and reduced need for repeat biopsies.

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Area of Science:

  • Urology
  • Oncology
  • Medical Imaging

Background:

  • Prostate cancer (PCA) diagnosis often relies on biopsies.
  • Accurate detection and risk stratification are crucial for effective treatment.
  • MRI/US fusion biopsy offers a potential improvement over traditional methods.

Purpose of the Study:

  • To evaluate the initial clinical experience with MRI/US fusion biopsy using the Koelis Trinity device.
  • To assess the diagnostic yield and safety of this technique in patients with suspected prostate cancer.

Main Methods:

  • A consecutive series of 59 patients with suspected PCA underwent MRI/US fusion biopsy.
  • Patients were divided into two groups: those with previous negative biopsies (Group A) and biopsy-naïve patients (Group B).
  • Data collected included patient demographics, PSA levels, MRI findings, and biopsy results.

Main Results:

  • Overall PCA detection rates were 45.5% in Group A and 37.8% in Group B.
  • Significant PCA (Gleason pattern 4) detection rates were 40% and 35.7% respectively.
  • MRI target biopsies were key in detecting significant cancer; random biopsies primarily found lower-grade cancers.

Conclusions:

  • MRI/US fusion biopsy using the Koelis Trinity device achieved comparable detection rates to existing literature.
  • The technique shows potential for improved risk stratification and reduced understaging.
  • This approach may decrease the need for repeat biopsies in both naïve and previously biopsied patients.