Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

2.6K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.6K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

432
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
432
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

2.2K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.2K
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

341
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
341
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

2.0K
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
2.0K
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

465
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
465

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Local regrowth: what are the surgical options?]

Chirurgie (Heidelberg, Germany)·2026
Same author

Letter to the Editor: 250th cardiac arrest center certification in Germany.

Clinical research in cardiology : official journal of the German Cardiac Society·2025
Same author

Laparoscopic vs. Robotic transabdominal adrenalectomy- propensity matched analysis and learning curve.

Langenbeck's archives of surgery·2025
Same author

Two-step versus three-step proctocolectomy for ulcerative colitis: a comparative study on nutritional status, immunosuppressive therapy, and long-term outcome.

Techniques in coloproctology·2024
Same author

[Abdominal compartment syndrome in visceral surgery and intensive care medicine : Causes, prevention, detection, treatment].

Chirurgie (Heidelberg, Germany)·2024
Same author

Rivaroxaban attenuates neutrophil maturation in the bone marrow niche.

Basic research in cardiology·2023

Related Experiment Video

Updated: Mar 9, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

6.1K

[Procedures on patients receiving NOACs : What's possible?]

A Polzin1, M Kelm2, P Horn2

  • 1Klinik für Kardiologie, Pneumologie und Angiologie, Universitätsklinikum der Heinrich-Heine-Universität Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland. amin.polzin@med.uni-duesseldorf.de.

Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|January 12, 2017
PubMed
Summary

Non-vitamin K antagonist oral anticoagulants (NOACs) are common for DVT, PE, and AF. This review guides perioperative management of NOACs based on drug properties, patient factors, and procedure risks.

Keywords:
AnticoagulantsBleedingIntensive carePerioperative carePharmacokinetics

More Related Videos

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.5K
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

84.7K

Related Experiment Videos

Last Updated: Mar 9, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

6.1K
Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.5K
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

84.7K

Area of Science:

  • Pharmacology
  • Cardiology
  • Hematology

Background:

  • Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly prescribed for deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF).
  • Current guidelines lack comprehensive data on managing patients on NOACs during interventional procedures, surgery, or in intensive care settings.

Purpose of the Study:

  • To review existing evidence and provide recommendations for optimal peri-interventional and perioperative antithrombotic management in patients taking NOACs.

Main Methods:

  • Literature review of studies and guidelines concerning NOACs.
  • Analysis of NOAC pharmacokinetics, patient-specific factors, bleeding risk, and procedural urgency.

Main Results:

  • Management strategies for NOACs depend on drug-specific pharmacokinetics, individual patient characteristics, and the bleeding risk associated with the planned intervention or surgery.
  • Recommendations are tailored based on the urgency of the procedure.

Conclusions:

  • Optimal peri-procedural management of patients on NOACs requires a personalized approach.
  • Further research is needed to establish definitive guidelines for NOAC management in specific clinical scenarios.