Effect of medical treatment on histological findings in rabbits with acute appendicitis
Related Experiment Video
Updated: Mar 9, 2026
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
Gürcan Şimşek, Barış Sevinç1, Yaşar Ünlü
1Department of General Surgery, Sarıkaya State Hospital, Yozgat-Turkey. drbarissevinc@gmail.com.
Background:
Acute appendicitis (AA) is the most common reason for abdominal surgery in the world. The aim of this study was to evaluate the effect of medical treatment on histological findings in rabbits with AA.
Methods:
Twenty-one male New Zealand rabbits were divided into 3 groups: appendix ligation and medical treatment, appendix ligation and no treatment, and control group, which underwent only laparotomy.
Results:
In appendix ligation without treatment group, AA findings were much more severe.
Conclusion:
Medical treatment reduced inflammation of AA.
Related Concept Videos
01:29Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
01:22Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...