Two-Dimensional Nanomaterials for Cancer Nanotheranostics

Area of Science:

• Nanotechnology
• Materials Science
• Oncology

Background:

• Two-dimensional nanomaterials (2DNMs) possess unique physicochemical properties beneficial for cancer theranostics.
• 2DNMs show potential in cancer detection, molecular imaging, and therapeutic applications like drug delivery and photothermal/photodynamic therapies.

Purpose of the Study:

• To review the current advancements in 2DNMs for cancer nanotheranostics.
• To discuss the challenges and strategies for enhancing 2NM biocompatibility in biomedical applications.

Main Methods:

• Comprehensive literature review of recent studies on 2DNMs in cancer theranostics.
• Analysis of modification strategies to improve the in vivo performance and safety of 2DNMs.

Main Results:

• 2DNMs demonstrate significant promise in various aspects of cancer diagnosis and therapy.
• Limited understanding of in vivo metabolism, transformation, and toxicity of 2DNMs poses a challenge for clinical translation.

Conclusions:

• 2DNMs represent a promising platform for developing next-generation cancer theranostic agents.
• Further investigation into the in vivo characteristics and biocompatibility of 2DNMs is crucial for their safe and effective clinical application.