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Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological
Chong Cheng1, Shuang Li2, Arne Thomas2
1Institute of Chemistry and Biochemistry, Freie Universität Berlin , Takustrasse 3, 14195 Berlin, Germany.
Chemical Reviews
|January 12, 2017
Summary
Functional graphene nanomaterials (FGNs) promote biological interactions by enhancing cell adhesion and growth. This review explores FGN applications in creating advanced bioactive platforms for diverse biological uses.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Cell Biology
Background:
- Functional graphene nanomaterials (FGNs) possess unique properties enabling interactions with biological systems.
- FGNs show potential in drug delivery, phototherapy, and bioimaging.
- Recent research highlights FGNs' ability to promote interfacial biointeractions with proteins, cells, and microbes.
Purpose of the Study:
- To review FGN-bioorganism interactions.
- To summarize advancements in designing FGN-based 2D and 3D architectures for biological applications.
- To discuss current and future perspectives in this emerging field.
Main Methods:
- Literature review of FGN-bioorganism interactions.
- Analysis of FGN-based bioactive architectures (2D and 3D).
- Discussion of representative biological applications and future challenges.
Main Results:
- FGNs concentrate nutritional factors, promoting extracellular matrix formation and cell colonization.
- FGNs stimulate cocultured cells, mediating cellular signaling and biological performance.
- FGNs serve as multifunctional platforms for diverse biological applications.
Conclusions:
- FGNs offer significant potential for biological applications due to their ability to modulate biointeractions.
- Designing FGN-based architectures is key to unlocking their multifunctional capabilities.
- Further research into FGN-bioorganism interactions will drive innovation in biomaterials and biotechnology.
