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HIV-associated sub-acute sclerosing panencephalitis - an emerging threat?
Abi Manesh1, Mahesh Moorthy2, Rini Bandopadhyay1
11 Department of Infectious Diseases, Christian Medical College, Vellore, India.
International Journal of STD & AIDS
|January 13, 2017
Summary
Measles virus infection at a younger age increases the risk of sub-acute sclerosing panencephalitis (SSPE), especially in children with HIV. This case highlights the unpredictable, severe presentation of SSPE in an HIV-infected young adult.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Measles virus infection, particularly at younger ages, is a known risk factor for sub-acute sclerosing panencephalitis (SSPE).
- The risk of SSPE is significantly elevated in children co-infected with human immunodeficiency virus (HIV).
- Recent measles outbreaks in populations with inadequate vaccine coverage raise concerns about potential increases in SSPE cases.
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