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Related Concept Videos

Reporter Genes02:11

Reporter Genes

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Project GENIE Goes Public

    Cancer Discovery
    |January 13, 2017
    PubMed
    Summary

    The American Association for Cancer Research released nearly 19,000 cancer genomic records from 59 cancer types. This large dataset is now publicly accessible for research, advancing cancer genomics and treatment discovery.

    Area of Science:

    • Oncology
    • Genomics
    • Bioinformatics

    Background:

    • Cancer research relies on large-scale genomic data.
    • Publicly accessible datasets accelerate discovery.
    • Genomic Evidence Neoplasia Information Exchange (GENIE) aims to facilitate this.

    Purpose of the Study:

    • To release a substantial, deidentified genomic dataset for public use.
    • To support research across 59 cancer types.

    Main Methods:

    • Collected deidentified genomic data from patients with cancer.
    • Data sourced from eight leading medical centers.
    • Compiled nearly 19,000 genomic records.

    Main Results:

    • Released almost 19,000 deidentified genomic records.

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  • Dataset covers 59 distinct types of cancer.
  • Represents one of the largest publicly accessible genomic data pools.

    • Conclusions:

    • The release of the GENIE dataset provides a valuable resource for cancer research.
    • Facilitates further investigation into cancer genomics and potential therapeutic targets.
    • Promotes collaborative research in oncology.