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Seroprevalence of Toxocariasis in Children with Urticaria: A Population-based Study

Paula Mayara Matos Fialho1, Carlos Roberto Silveira Correa1, Susana Zevallos Lescano2

  • 1Faculdade de Ciências Médicas, Departamento de Saúde Coletiva, Campinas, São Paulo, Brasil.

Journal of Tropical Pediatrics
|January 13, 2017
PubMed

Insights

This study found a link between Toxocara infection and urticaria in children. Higher rates of toxocariasis (16%) were seen in children with hives, suggesting a connection.

Area of Science:

  • Pediatric Allergy and Immunology
  • Infectious Diseases
  • Epidemiology

Background:

  • Urticaria is a common skin condition in children.
  • Toxocariasis, a parasitic infection, is often asymptomatic but can cause various symptoms.
  • The relationship between Toxocara infection and urticaria requires further investigation.

Purpose of the Study:

  • To determine the prevalence of IgG antibodies against Toxocara species in children aged 2-12 years.
  • To investigate the association between Toxocara infection and the presence of urticaria in this pediatric population.

Main Methods:

  • A population-based cross-sectional study was conducted with 168 children.
  • Enzyme-Linked Immunosorbent Assay (ELISA) was used to detect IgG antibodies for toxocariasis.
  • Guardians were interviewed to collect data on urticaria and other health conditions.

Main Results:

  • The seroprevalence of toxocariasis was 16% among the children studied.
  • Urticaria was present in 38% of the participants.
  • A significant positive association was found between urticaria and positive Toxocara serology.

Conclusions:

  • This study provides the first population-based evidence correlating urticaria with serological evidence of toxocariasis in children.
  • The findings suggest that Toxocara infection may play a role in the development of urticaria in pediatric populations.
  • Further research is warranted to elucidate the mechanisms underlying this association.
Abstract

Keywords:
epidemiologypediatricstoxocariasistropical medicineurticaria

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