Related Experiment Video
Updated: Mar 9, 2026
04:58
Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
Published on: December 13, 2024
4.4K
Erratum to: A bedr way of genomic interval processing
Syed Haider1, Daryl Waggott1, Emilie Lalonde1,2
1Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, M5G 0A3 Canada.
Source Code for Biology and Medicine
|January 13, 2017
Summary
This study corrects a previously published article DOI. The correction ensures accurate citation and referencing for scientific research. This enhances data integrity and reproducibility in the field.
Area of Science:
- Scientific publishing
- Scholarly communication
- Research integrity
Context:
- Correction of a previously assigned Digital Object Identifier (DOI).
- Ensuring accurate referencing for a scientific article.
- Maintaining the integrity of the scientific record.
Purpose:
- To provide the correct DOI for the article.
- To prevent misattribution and facilitate proper citation.
- To uphold standards in scientific communication.
Summary:
- The article DOI has been updated to 10.1186/s13029-016-0059-5.
- This correction ensures that readers and databases can accurately locate and cite the research.
- This action rectifies a previous error in the article's metadata.
Impact:
- Improved discoverability of the scientific work.
- Enhanced accuracy in academic databases and citation indexes.
- Reinforcement of trust and reliability in published research.
Related Concept Videos
01:57Sanger Sequencing
776.6K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
776.6K
02:37Gene Duplication and Divergence
8.1K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
8.1K
02:46Genome Copying Errors
5.3K
DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their survival. Therefore, the copying errors are checked and repaired at three levels.
5.3K
00:58Genomic DNA in Eukaryotes
53.6K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
53.6K
03:00Next-generation Sequencing
100.0K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
100.0K
01:02Long-patch Base Excision Repair
8.2K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.2K