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Cardiobacterium hominis and Cardiobacterium valvarum: Two Case Stories with Infective Episodes in Pacemaker Treated
Tina Bennett Bonavent1, Xiaohui Chen Nielsen2, Kjeld Skødebjerg Kristensen1
1Department of Internal Medicine, Holbæk Hospital, Holbæk, Denmark.
Insights
Cardiobacterium species can cause rare infective endocarditis in patients with cardiac devices. These cases highlight diverse disease severity and the need for vigilant follow-up to detect relapsing infections.
Area of Science:
- Infectious Diseases
- Cardiology
- Medical Microbiology
Background:
- Cardiobacterium hominis and Cardiobacterium valvarum are rare causes of infective endocarditis.
- Increasing prevalence of cardiac device implantation.
Purpose of the Study:
- To present two cases of infective endocarditis caused by Cardiobacterium species in patients with cardiac pacemakers.
- To illustrate the spectrum of disease presentation and management.
Main Methods:
- Case report of two patients with pacemaker-treated infective endocarditis.
- Blood cultures, echocardiography, and device management were utilized.
Main Results:
- One patient experienced relapsing Cardiobacterium hominis infection over two years, requiring device and lead removal.
- The second patient with Cardiobacterium valvarum presented with a large vegetation on a bicuspid aortic valve.
Conclusions:
- Cardiobacterium species exhibit diverse disease severity in infective endocarditis.
- Close patient follow-up is crucial to identify silent, relapsing infections, especially in those with cardiac devices.
Introduction:
Cardiobacterium hominis and Cardiobacterium valvarum are well known, though rare, etiologic agents of infective endocarditis. Cardiac devices are increasingly implanted.
Case Reports:
Two cases of infective episodes in pacemaker (PM) treated patients with respectively C. hominis and C. valvarum are presented. In one case blood-culture bottles yielded growth of C. hominis at two episodes with two years apart. At the second episode a vegetation was recognized at the PM lead and the PM device and lead was removed. In the C. valvarum case, echocardiography revealed a bicuspid aortic valve with severe regurgitation and a more than 1 cm sized vegetation.
Conclusion:
The cases illustrate the diversity in disease severity by Cardiobacterium species. Careful follow up has to be performed in order not to overlook a relatively silent relapsing infection.
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