Effects of etomidate and propofol on immune function in patients with lung adenocarcinoma
Jiapeng Liu1, Wei Dong1, Tao Wang1
1Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
Objective:
To investigate the effects of etomidate and propofol on immune function in patients with lung adenocarcinoma.
Methods:
Sixty patients who were scheduled for lung cancer surgery under general anesthesia were studied. The patients were randomly divided into an etomidate total intravenous anesthesia group (group E) and a propofol total intravenous anesthesia group (group P), with 30 cases in each group.
Results:
Within group comparison: The percentage of CD4+ in the two groups was significantly reduced at 24 hours post-operation (T2) compared with the percentage before surgery, whereas the percentage of CD8+ was higher at T2. Between group comparison: The CD4+ percentage of group E was higher than that of group P (P < 0.05) at T2, whereas the CD8+ percentage was lower than that of group P (P < 0.05) at T1.
Conclusion:
Using etomidate for anesthesia has less of an effect on immune function in patients with lung adenocarcinoma.
More Related Videos
Related Concept Videos
Parenteral Anesthetics: Overview
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...


