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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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Dengue Fever-Associated Maculopathy and Panuveitis in Australia.
K G-J Ooi1, H Inglis1, N Paramanathan1
1Department of Ophthalmology, Prince of Wales Hospital, Barker Street, Randwick, NSW 2031, Australia.
Case Reports in Ophthalmological Medicine
|January 13, 2017
Summary
Dengue fever can cause serious eye problems like maculopathy and panuveitis. Early detection and awareness are crucial for preventing vision loss from these rare dengue complications.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Dengue fever outbreaks are increasing in Australia.
- Ophthalmic complications of dengue, though rare, can be sight-threatening.
Observation:
- A case of bilateral dengue fever-associated maculopathy with left panuveitis is presented.
- The patient experienced paracentral scotomas and specific maculopathy types (diffuse retinal thickening and acute macular neuroretinopathy).
Findings:
- Clinical and hematological diagnosis confirmed dengue-associated maculopathy and panuveitis.
- Optical coherence tomography revealed distinct maculopathy presentations in each eye.
- Conservative treatment with topical steroids and cycloplegia resulted in full visual recovery.
Implications:
- Highlights the importance of recognizing ophthalmic complications of dengue fever.
- Increased incidence of these complications is anticipated in Australia due to climate change and mosquito distribution.
- Emphasizes the need for heightened awareness among clinicians regarding potential ocular manifestations of dengue.
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