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Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test
M H Grunwald1, S Halevy, E Livni
1Department of Dermatology, Soroka Medical Center, Beer Sheva, Israel.
Israel Journal of Medical Sciences
|October 1, 1989
Summary
Hydrochlorothiazide, a diuretic, may cause allergic vasculitis. A positive mast cell degranulation test suggests a role for in vitro tests in diagnosing drug-induced skin reactions.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Allergic vasculitis is an inflammatory condition affecting blood vessels.
- Drug-induced eruptions are a common clinical challenge.
- Hydrochlorothiazide is a widely prescribed diuretic.