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Updated: Mar 8, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Gastric and jejunal histopathological changes in patients undergoing bariatric surgery
Rosemary Simões Nomelini Rodrigues1, Élia Cláudia de Souza Almeida1, Júverson Alves Terra1
1Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brasil.
Background:
- Morbid obesity is a multifactorial disease that is increasingly treated by surgery.
Objective:
- To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery.
Methods:
- This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative.
Results:
- In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in Helicobacter pylori infection (P=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%.
Conclusion:
- There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients.
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