Related Experiment Video
Updated: Mar 8, 2026
A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Clinical Experience: Using Dehydrated Human Amnion/Chorion Membrane Allografts for Acute and Reconstructive Burn Care
Debra Ann Reilly1, Sean Hickey, Paul Glat
1From the *Division of Plastic Surgery, University of Nebraska Medical Center, Omaha, NE; †Sumner Redstone Burn Center, Department of Surgery, Massachusetts General Hospital, Boston, MA; ‡Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, PA; and §Joseph M. Still Burn and Reconstructive Center, Jackson, MS.
Abstract:
Amniotic membrane is immunologically privileged and is a reservoir of growth factors and cytokines known to modulate inflammation and enhance the healing process, while also possessing antimicrobial, antifibrosis, and antiscarring properties. These properties establish a strong argument for using amniotic membrane derived products as a treatment for burns. The purpose of this article is to describe the use of commercially available dehydrated human amnion/chorion membrane allografts in patients with partial-thickness and full-thickness burns.
Related Concept Videos
01:22Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
01:19Clinical Applications of Epidermal Stem Cells