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2017 European guideline for the management of chancroid

Stephan Lautenschlager1, Michael Kemp2, Jens Jørgen Christensen3

  • 11 Outpatient Clinic of Dermatology & Venereology, City Hospital Triemli, Zurich, Switzerland.

International Journal of STD & AIDS
|January 14, 2017
PubMed

Insights

Chancroid, a genital ulcer infection caused by Haemophilus ducreyi, presents diagnostic challenges. Nucleic acid amplification tests aid in detection, and antibiotics are effective treatments for this sexually transmitted infection.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Dermatology

Background:

  • Chancroid is a sexually transmitted infection caused by the bacterium Haemophilus ducreyi.
  • It manifests as painful genital ulcers and swollen lymph nodes (buboes).
  • Diagnosis can be difficult due to the pathogen's rarity in some regions and challenges in laboratory culture.

Purpose of the Study:

  • To review the characteristics and diagnosis of chancroid.
  • To highlight the utility of nucleic acid amplification tests (NAATs) for H. ducreyi detection.
  • To emphasize effective treatment strategies for chancroid.

Main Methods:

  • Review of existing literature on Haemophilus ducreyi and chancroid.
  • Discussion of diagnostic methods, including culture and NAATs.
  • Summary of antibiotic treatment regimens.

Main Results:

  • Haemophilus ducreyi is the causative agent of chancroid.
  • Genital ulcers and lymphadenitis are key clinical features.
  • Nucleic acid amplification tests offer improved sensitivity for detecting H. ducreyi compared to traditional culture.

Conclusions:

  • Chancroid requires accurate identification due to potential misdiagnosis.
  • NAATs are valuable tools for confirming H. ducreyi infections.
  • Antibiotic therapy is the standard and effective treatment for chancroid.

Keywords:
Haemophilus ducreyichancroidsexually transmitted infection

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