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Vaccination against infectious bronchitis virus: A continuous challenge.

Brian Jordan1

  • 1Department of Population Health, Poultry Diagnostic and Research Center, College of Veterinary Medicine, The University of Georgia, 953 College Station Rd., Athens, GA, 30602, USA; Department of Poultry Science, College of Agricultural and Environmental Sciences, The University of Georgia, 210 Cedar St., Athens, GA, 30602, USA.

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Summary

Infectious bronchitis virus (IBV) poses a major threat to poultry, with current vaccines often failing due to emerging variants. New vaccine technologies are needed for effective IBV control in commercial poultry production.

Keywords:
Infectious bronchitis virusVaccinationVaccine

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Area of Science:

  • Veterinary Virology
  • Poultry Health
  • Immunology

Background:

  • Infectious bronchitis virus (IBV) is a major cause of economic loss in the global poultry industry.
  • Existing vaccination strategies for IBV are often inefficient and lead to frequent failures.
  • The continuous emergence of new IBV serotypes and variants complicates disease control efforts.

Purpose of the Study:

  • To review the current challenges in controlling infectious bronchitis virus (IBV) in commercial poultry.
  • To discuss existing vaccination practices, vaccine efficacy, and the development of immunity against IBV.
  • To highlight recent advancements in vaccine technology that could offer improved protection against IBV.

Main Methods:

  • This review synthesizes current literature on IBV control strategies.
  • It examines the limitations of current IBV vaccines and vaccination methods.
  • It explores emerging vaccine technologies and their potential impact on poultry health.

Main Results:

  • Current IBV vaccines face challenges due to serotype diversity and vaccination failures.
  • Understanding IBV protein and host cell interactions is crucial for developing targeted interventions.
  • Novel vaccine technologies show promise for enhancing protection against IBV.

Conclusions:

  • Effective control of infectious bronchitis virus (IBV) remains a significant challenge in the poultry industry.
  • Advancements in vaccine technology and a deeper understanding of virus-host interactions are essential for future IBV prevention.
  • Improved vaccine strategies are critical to mitigate economic losses associated with IBV outbreaks.