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Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
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Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

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Evolution and Increasing Complexity of the Therapeutic Landscape in Advanced Non-Small-cell Lung Cancer

David R Gandara1, Jonathan W Riess1, Karen Kelly1

  • 1University of California, Davis, Comprehensive Cancer Center, Sacramento, CA.

Clinical Lung Cancer
|January 14, 2017
PubMed

Insights

The treatment options for advanced non-small-cell lung cancer (NSCLC) are rapidly evolving, making treatment decisions more complex for oncologists. This perspective reviews these significant changes in the NSCLC therapeutic landscape.

Area of Science:

  • Oncology
  • Medical Therapeutics

Background:

  • The treatment landscape for advanced non-small-cell lung cancer (NSCLC) is undergoing unprecedented and rapid transformation.
  • This evolution presents significant challenges in clinical decision-making for oncologists.

Purpose of the Study:

  • To describe the rapid evolution of therapeutic options in advanced non-small-cell lung cancer (NSCLC).
  • To highlight the increasing complexity in treatment selection for practicing oncologists.

Main Methods:

  • This is a perspective piece, not an original research study.
  • It synthesizes current trends and expert insights into the changing NSCLC treatment paradigm.

Main Results:

  • The field of advanced NSCLC therapeutics has seen numerous major advancements recently.
  • The complexity of choosing the optimal treatment strategy has increased substantially.

Conclusions:

  • Practicing oncologists face a dynamic and complex environment when managing advanced NSCLC.
  • Understanding these rapid changes is crucial for effective patient care in NSCLC.
Keywords:
Epidermal growth factor receptorNSCLCTargeted therapyTherapeutic landscapeTyrosine kinase inhibitor

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