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Myocardial Infarction and Functional Outcome Assessment in Pigs
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Clinical outcomes in myocardial infarction and multivessel disease after a cardiac rehabilitation programme: Partial

Ricardo Mori Junco1, Regina Dalmau Gonzalez-Gallarza2, Almudena Castro Conde2

  • 1Servicio de Cardiología, Hospital Universitario La Paz, 261, Paseo de la Castellana, 28046 Madrid, Spain.

Archives of Cardiovascular Diseases
|January 14, 2017
PubMed

Insights

Complete revascularization (CR) showed no significant clinical outcome differences compared to partial revascularization (PR) in ST-segment elevation myocardial infarction (STEMI) patients undergoing cardiac rehabilitation. Both strategies yielded similar rates of cardiovascular events and mortality during follow-up.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Rehabilitation

Background:

  • Current guidelines recommend culprit vessel percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) with multivessel disease.
  • Emerging evidence suggests improved outcomes with multivessel PCI.

Purpose of the Study:

  • To compare clinical outcomes between partial revascularization (PR) and complete revascularization (CR) in STEMI patients with multivessel disease.
  • To assess the impact of PR versus CR within a cardiac rehabilitation program.

Main Methods:

  • Retrospective review of 282 STEMI patients with multivessel disease who underwent PR or CR.
  • Inclusion in a cardiac rehabilitation program between July 2006 and November 2013.
  • Comparison of cardiovascular events, new PCI, hospital admissions, and mortality between groups.

Main Results:

  • 143 patients received PR, and 139 received CR; baseline characteristics were similar, with minor differences in age, diabetes, and number of stenotic arteries.
  • Over a mean follow-up of 48 months, cardiovascular events occurred in 16.1% of PR patients and 14.4% of CR patients (no significant difference).
  • Adjusted Cox regression analysis revealed no difference in new cardiovascular event risk between PR and CR groups.

Conclusions:

  • No statistically significant differences in clinical outcomes were observed between partial revascularization and complete revascularization.
  • These findings suggest that both PR and CR are viable strategies for STEMI patients with multivessel disease within a cardiac rehabilitation setting.
Abstract

Keywords:
AngioplastieAngioplastyCoronaropathieCoronary artery diseaseInfarctus du myocardeMyocardial infarctionPrognosisPronosticRehabilitationRéadaptation

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