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Standard Operating Procedure for Lyssavirus Surveillance of the Bat Population in Taiwan
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Complete Genome Sequence of Lleida Bat Lyssavirus
Denise A Marston1,2, Richard J Ellis3, Emma L Wise1
1Wildlife Zoonoses & Vector-Borne Diseases Research Group, Animal and Plant Health Agency (APHA), Surrey, United Kingdom.
Genome Announcements
|January 14, 2017
Summary
A novel virus, Lleida bat lyssavirus (LLEBV), has been identified in bats. This discovery is significant as all lyssaviruses cause rabies, a fatal neurological disease with no cure once symptoms appear.
Area of Science:
- Virology
- Infectious Diseases
- Neuroscience
Background:
- Lyssaviruses, belonging to the Rhabdoviridae family, are known to cause rabies.
- Rabies is an acute, progressive encephalitis with no effective cure once clinical symptoms manifest.
- Bats are a known reservoir for various lyssavirus strains.
Purpose of the Study:
- To report the discovery and full-genome sequencing of a novel lyssavirus.
- To characterize a new virus identified in a common bent-winged bat.
Main Methods:
- Next-generation sequencing (NGS) was employed for full-genome sequencing.
- Analysis of brain tissue from a common bent-winged bat.
Main Results:
- The full-genome sequence of a novel lyssavirus, Lleida bat lyssavirus (LLEBV), was confirmed.
- The virus was isolated from the brain of a common bent-winged bat.
Conclusions:
- A new lyssavirus, LLEBV, has been identified, expanding the known diversity of rabies-causing viruses.
- This finding underscores the importance of continued surveillance for novel viral agents in wildlife reservoirs.
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