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Related Experiment Videos

Monoamine oxidase inhibitor toxicity.

B Pfefferbaum, R Pack, J van Eys

    Journal of the American Academy of Child and Adolescent Psychiatry
    |November 1, 1989
    PubMed
    Summary

    Monoamine oxidase inhibitor (MAOI) drugs, like procarbazine, can cause toxic effects in children treated for CNS tumors. This case highlights MAOI risks and potential drug interactions in pediatric oncology.

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    Area of Science:

    • Oncology
    • Pharmacology
    • Pediatrics

    Background:

    • Monoamine oxidase inhibitors (MAOIs) are utilized for treating depressive and anxiety disorders in adults.
    • High doses of MAOIs are also employed in pediatric treatment protocols for lymphomas and central nervous system (CNS) tumors.