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Early nasogastric feeding versus parenteral nutrition in severe acute pancreatitis: A retrospective study

Yulong Tao1, Chengwu Tang2, Wenming Feng3

  • 1Dr. Yulong Tao, MD, Department of General Surgery, First People's Hospital affiliated to Huzhou University Medical College, Huzhou, Zhejiang Province, China.

Pakistan Journal of Medical Sciences
|January 14, 2017
PubMed

Insights

Early nasogastric enteral nutrition (EN) significantly reduced infections, multiple organ dysfunction syndrome (MODS), and mortality in severe acute pancreatitis (SAP) patients compared to total parenteral nutrition (TPN). EN also shortened hospital stays.

Area of Science:

  • Gastroenterology
  • Critical Care Medicine
  • Surgical Nutrition

Background:

  • Severe acute pancreatitis (SAP) management requires optimal nutritional support.
  • Enteral nutrition (EN) and total parenteral nutrition (TPN) are common modalities.
  • The optimal timing and type of nutritional intervention in SAP remain debated.

Purpose of the Study:

  • To compare the efficacy and safety of early nasogastric EN versus TPN in SAP patients.
  • To evaluate the impact of nutritional strategies on infectious complications, organ dysfunction, and mortality.

Main Methods:

  • Retrospective study of 185 SAP patients (July 2008-July 2014).
  • Patients allocated to nasogastric EN (n=89) or TPN (n=96) within 72 hours of onset.
  • Analysis of clinical factors, complications, hospital stay, and mortality.

Main Results:

  • EN group showed significantly lower rates of pancreatic and extrapancreatic infections.
  • EN group experienced shorter hospital and intensive care unit (ICU) stays.
  • TPN group had higher incidence of multiple organ dysfunction syndrome (MODS) and mortality, with increased hyperglycemia.

Conclusions:

  • Early nasogastric EN is a feasible and effective nutritional strategy for SAP.
  • EN significantly reduces infectious complications, MODS, and mortality in SAP.
  • EN offers advantages over TPN in managing severe acute pancreatitis.
Abstract

Keywords:
Enteral NutritionSevere Acute PancreatitisTotal Parenteral Nutrition

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