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Published on: January 17, 2025
Idiopathic infantile arterial calcification: a case report of successful extracorporeal membrane oxygenation support
Shriprasad R Deshpande1, Gangajal Kasniya1, Angel R Cuadrado1
1Division of Pediatric Cardiology, Children's Healthcare of Atlanta, Emory University, Atlanta, GA - USA.
Insights
Idiopathic infantile arterial calcification (IIAC) is a rare condition causing heart failure in infants. This case report details the first successful use of extracorporeal membrane oxygenation and etidronate treatment for a critically ill infant with IIAC.
Area of Science:
- Pediatric Cardiology
- Neonatology
- Rare Diseases
Background:
- Idiopathic infantile arterial calcification (IIAC) is a rare condition leading to severe infantile ischemic cardiac failure.
- IIAC has an extremely poor prognosis, posing significant challenges in management.
Abstract:
Idiopathic infantile arterial calcification is a rare cause of infantile ischemic cardiac failure with extremely poor prognosis. We present the first case report of successful extracorporeal membrane oxygenation support and outcome in a child with idiopathic infantile arterial calcification (IIAC). This 6-week-old infant presented with cardiogenic shock and circulatory collapse. The patient underwent extracorporeal cardiopulmonary resuscitation, allowing stabilization, diagnosis, and treatment with etidronate, followed by successful discharge to home.

