Related Experiment Video

Updated: Mar 8, 2026

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.6K

Resting heart rate associated with survival in diabetes

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |January 15, 2017
    PubMed

    Insights

    Resting heart rate is linked to cardiovascular events in patients with coronary artery disease and diabetes. Monitoring heart rate may help predict risks for these serious conditions.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Preventive Medicine

    Background:

    • Coronary artery disease (CAD) and diabetes mellitus (DM) are major risk factors for cardiovascular events.
    • Resting heart rate (RHR) is an easily measurable physiological parameter.
    • Elevated RHR has been suggested as a potential marker for cardiovascular risk.

    Purpose of the Study:

    • To investigate the association between resting heart rate and the occurrence of major adverse cardiovascular events (MACE) in patients with both CAD and DM.

    Main Methods:

    • A retrospective cohort study design was employed.
    • Data from patients with diagnosed CAD and DM were analyzed.
    • Resting heart rate was recorded at baseline, and follow-up was conducted for cardiovascular events.

    Main Results:

    • A statistically significant association was found between higher resting heart rate and an increased risk of cardiovascular events.
    • The association remained significant after adjusting for traditional cardiovascular risk factors.

    Conclusions:

    • Resting heart rate is a significant independent predictor of cardiovascular events in patients with coronary artery disease and diabetes.
    • RHR monitoring could be a valuable tool for risk stratification and management in this high-risk population.

    More Related Videos

    Assessment of Sarcoplasmic Reticulum Calcium Reserve and Intracellular Diastolic Calcium Removal in Isolated Ventricular Cardiomyocytes11:00

    Assessment of Sarcoplasmic Reticulum Calcium Reserve and Intracellular Diastolic Calcium Removal in Isolated Ventricular Cardiomyocytes

    Published on: September 18, 2017

    10.7K
    Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach07:49

    Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach

    Published on: July 21, 2023

    2.0K

    Related Concept Videos

    Factors Influencing Heart Rate01:30

    Factors Influencing Heart Rate

    The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
    Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
    7.1K
    Regulation of Heart Rates01:31

    Regulation of Heart Rates

    The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
    The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
    4.3K
    Diabetes: Symptoms, Diagnosis, and Complications01:15

    Diabetes: Symptoms, Diagnosis, and Complications

    For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
    2.6K
    Hypoglycemia and Glucagon01:15

    Hypoglycemia and Glucagon

    Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
    1.1K
    Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

    Cardiac Output I:Effect of Heart Rate on Cardiac Output

    Cardiac Output
    Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
    Effect of Heart Rate on Cardiac Output
    Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
    3.1K
    Carbohydrate Metabolism01:36

    Carbohydrate Metabolism

    Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
    Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
    14.7K