Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

94
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
94
Allergic Reactions02:06

Allergic Reactions

33.1K
Overview
33.1K
Pharmacovigilance01:19

Pharmacovigilance

1.9K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

68
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
68
Data Reporting and Recording01:24

Data Reporting and Recording

5.6K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.6K
Drug Regulation01:25

Drug Regulation

3.2K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epigenetic gestational age acceleration and indicators of BMI trajectories in childhood.

Scientific reports·2026
Same author

EAACI Guidelines on Environmental Science for Allergy and Asthma-Evidence-Based Recommendations for Prevention and Public Health Action to Mitigate the Impact of Pollen Exposure on Respiratory Allergy.

Allergy·2026
Same author

Occupational category, job type, and sarcoidosis: Findings from a French multicenter study.

Pulmonology·2026
Same author

Respiratory impacts of earthquakes.

European respiratory review : an official journal of the European Respiratory Society·2026
Same author

Toxic skies of war.

The Lancet. Respiratory medicine·2026
Same author

Microplastic accumulation in the human lung: distinct signatures in lung cancer vs normal tissue.

American journal of respiratory and critical care medicine·2026

Related Experiment Video

Updated: Mar 8, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.4K

Fatal anaphylaxis registries data support changes in the who anaphylaxis mortality coding rules.

Luciana Kase Tanno1,2,3, F Estelle R Simons4, Isabella Annesi-Maesano5

  • 1Hospital Sírio Libanês, São Paulo, Brazil. luciana.tanno@gmail.com.

Orphanet Journal of Rare Diseases
|January 15, 2017
PubMed
Summary
This summary is machine-generated.

Coding challenges for anaphylaxis deaths lead to undercounting severe allergic reactions. This review advocates for including anaphylaxis as a cause of death on international certificates to improve reporting accuracy.

Keywords:
AnaphylaxisClassificationInternational Classification of DiseasesMortalityWorld Health Organization

More Related Videos

Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

20.1K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.7K

Related Experiment Videos

Last Updated: Mar 8, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.4K
Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

20.1K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.7K

Area of Science:

  • Medical Science
  • Public Health
  • Allergy and Immunology

Background:

  • Anaphylaxis is a severe, life-threatening hypersensitivity reaction.
  • Current coding systems, like the World Health Organization's International Classification of Diseases (ICD), hinder accurate reporting of anaphylaxis fatalities.
  • Anaphylaxis is not explicitly listed as an underlying cause of death on death certificates.

Purpose of the Study:

  • To review evidence supporting the need for changes in WHO mortality coding rules.
  • To advocate for the inclusion of anaphylaxis as an underlying cause of death on international death certificates.
  • To support a formal request to the WHO for this coding revision, particularly concerning the 11th ICD revision.

Main Methods:

  • Literature review of existing evidence on anaphylaxis mortality coding.
  • Analysis of current WHO ICD coding rules and death certificate limitations.
  • Formulation of arguments for policy change.

Main Results:

  • The current ICD system inadequately captures anaphylaxis deaths due to coding limitations.
  • Death certificates do not allow for 'anaphylaxis' as a primary cause of death.
  • Under-notification of anaphylaxis fatalities is a significant public health concern.

Conclusions:

  • Changes to WHO mortality coding rules are necessary to accurately reflect anaphylaxis deaths.
  • Adding anaphylaxis as an underlying cause of death on international certificates is crucial.
  • Improved coding will enhance public health surveillance and understanding of anaphylaxis fatalities.