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HGDB: A web retrieving cardiovascular-associated gene data.

Faezeh Noorabad-Ghahroodi1, Samaneh Abdi2, Amir Hossein Zand3

  • 1Biochemistry Department, School of Medicine, Shiraz University of Medical Sciences, Iran.

International Journal of Cardiology
|January 15, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces the Human Genome Database (HGDB), a new online resource for cardiovascular gene data. It provides an accessible platform for exploring molecular features of genes linked to cardiovascular diseases.

Keywords:
Cardiovascular diseaseDatabaseGeneHGDB

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Area of Science:

  • Genetics and Bioinformatics
  • Molecular Biology
  • Cardiovascular Research

Background:

  • High-throughput techniques generate vast genetic data crucial for biological studies.
  • Effective data management strategies like networking and enrichment are vital.
  • Cardiovascular diseases necessitate detailed genetic information for research and treatment.

Purpose of the Study:

  • To annotate molecular features of cardiovascular-associated genes.
  • To develop and present the HGDB, a searchable online database (www.hgdb.ir).
  • To facilitate access to comprehensive gene data for cardiovascular research.

Main Methods:

  • Utilized Gene Ontology as the primary data source.
  • Enriched initial data with additional molecular features.
  • Managed the integrated dataset using a popular, open-source SQL database.

Main Results:

  • Developed the HGDB with user-friendly search functionalities.
  • Implemented search options including gene ID/Name, chromosome, and cell organelle.
  • Presented search results with text-based and source link-based gene descriptions.

Conclusions:

  • The HGDB offers a user-friendly web interface for cardiovascular gene data.
  • The database serves as a valuable resource for researchers in the cardiovascular field.
  • HGDB enhances the accessibility and usability of complex genetic information.