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Antituberculosis drugs: reducing efflux=increasing activity.

Liliana Rodrigues1, Tanya Parish2, Meenakshi Balganesh3

  • 1Grupo de Genética de Micobacterias, Departamento de Microbiología, Medicina Preventiva y Salud Pública, Facultad de Medicina and BIFI, Universidad de Zaragoza, Zaragoza, Spain; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain; Fundación Agencia Aragonesa para la Investigación y Desarrollo (ARAID), Zaragoza, Spain.

Drug Discovery Today
|January 17, 2017
PubMed
Summary

Efflux pumps play a significant role in multidrug-resistant tuberculosis. Understanding drug efflux is crucial for developing new tuberculosis treatments and avoiding drug resistance.

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