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Published on: June 11, 2012
Euglycemic Diabetic Ketoacidosis with Persistent Diuresis Treated with Canagliflozin
Junichiro Adachi1, Yuusuke Inaba, Chisato Maki
1Department of Internal Medicine, Ohkubo Hospital, Japan.
Abstract:
Diabetic ketoacidosis is characterized by hyperglycemia, anion-gap acidosis, and increased plasma ketones. After the resolution of hyperglycemia, persistent diuresis is rare. We herein report the case of a 27-year-old Asian woman with type 2 diabetes who was treated with a sodium-glucose cotransporter 2 (SGLT2) inhibitor (canagliflozin) who developed euglycemic diabetic ketoacidosis and persistent diuresis in the absence of hyperglycemia. Physicians should consider euglycemic diabetic ketoacidosis in the differential diagnosis of patients treated with SGLT2 inhibitors.
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