Related Experiment Video
Updated: Mar 8, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Improving timeliness for acute asthma care for paediatric ED patients using a nurse driven intervention: an
Kathleen Brown1, Sabah Iqbal1, Su-Lin Sun1
1Children's National Health System, USA.
Insights
A new nurse-led protocol significantly reduced corticosteroid administration time for paediatric asthma exacerbations in the emergency department (ED), improving patient outcomes and lowering admission rates.
Area of Science:
- Emergency Medicine
- Paediatric Care
- Respiratory Medicine
Background:
- Asthma is a leading cause of paediatric emergency department (ED) visits.
- Timely corticosteroid administration is crucial for managing asthma exacerbations but often delayed in busy EDs.
Purpose of the Study:
- To decrease the time to corticosteroid administration for paediatric asthma exacerbations in a large, academic ED.
- To evaluate the impact of a nurse-initiated corticosteroid protocol on key process and balance measures.
Main Methods:
- An interrupted time series analysis was used for patients aged 1-18 with moderate to severe asthma exacerbations.
- A multidisciplinary team implemented a bedside nurse-initiated oral dexamethasone protocol, replacing physician-ordered prednisone.
- Data were collected over 12-month baseline and intervention periods, analyzed using statistical process control.
Main Results:
- Mean time to corticosteroid administration decreased significantly from 98 to 59 minutes (p < 0.01).
- The intervention led to a significant reduction in ED admission rates (p < 0.01) and emesis rates (p < 0.01).
- No adverse effects were observed in balance measures, including 5-day return visits or admissions.
Conclusions:
- A standardized, nurse-initiated corticosteroid protocol effectively and safely reduces treatment delays for paediatric asthma exacerbations.
- This intervention improves ED efficiency by lowering admission rates and associated complications like emesis.
- The protocol demonstrates sustained improvement and process stability, offering a model for other pediatric EDs.
Abstract:
Asthma is the most common chronic paediatric disease treated in the emergency department (ED). Rapid corticosteroid administration is associated with improved outcomes, but our busy ED setting has made it challenging to achieve this goal. Our primary aim was to decrease the time to corticosteroid administration in a large, academic paediatric ED. We conducted an interrupted time series analysis for moderate to severe asthma exacerbations of one to 18 year old patients. A multidisciplinary team designed the intervention of a bedside nurse initiated administration of oral dexamethasone, to replace the prior system of a physician initiated order for oral prednisone. Our baseline and intervention periods were 12 month intervals. Our primary process measure was the time to corticosteroid administration. Other process measures included ED length of stay, admission rate, and rate of emesis. The balance measures included rate of return visits to the ED or clinic within five days, as well as the proportion of discharged patients who were admitted within five days. No special cause variation occurred in the baseline period. The mean time to corticosteroid administration decreased significantly, from 98 minutes in the baseline period to 59 minutes in the intervention period (p < 0.01), and showed special cause variation improvement within two months after the intervention using statistical process control methodology. We sustained the improvement and demonstrated a stable process. The intervention period had a significantly lower admission rate (p<0.01) and emesis rate (p<0.01), with no unforeseen harm to patients found with any of our balance measures. In summary, the introduction of a nurse initiated, standardized protocol for corticosteroid therapy for asthma exacerbations in a paediatric ED was associated with decreased time to corticosteroid administration, admission rates, and post-corticosteroid emesis.
Related Concept Videos
Asthma-IV: Nursing Management
First, in...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Inhaled Medications
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...

