Related Experiment Video
Updated: Mar 8, 2026
07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
20.0K
Pituitary Macrotumor Causing Narcolepsy-Cataplexy in a Dachshund
S Schmid1, A Hodshon1, S Olin1
1Department of Small Animal Clinical Sciences, The University of Tennessee College of Veterinary Medicine, Knoxville, TN.
Journal of Veterinary Internal Medicine
|January 17, 2017
Summary
A pituitary tumor caused narcolepsy-cataplexy in a Dachshund, distinct from genetic causes. Treatment with stereotactic radiotherapy resolved symptoms, suggesting intracranial mass effect as a potential cause.
Area of Science:
- Veterinary Neurology
- Neuroscience
- Endocrinology
Background:
- Narcolepsy in dogs is typically linked to hypocretin receptor 2 gene mutations or hypocretin ligand deficiencies.
- Sporadic narcolepsy cases require investigation into less common etiologies.
Related Concept Videos
01:07Narcolepsy
674
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
674
01:24Sleep-Wake Cycles
3.1K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
3.1K