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Published on: November 17, 2018
In-hospital statin underutilization among high-risk patients: delayed uptake of the 2013 cholesterol guidelines in a
Subeer K Wadia1, Mark Belkin2, Kelsey S Chow3
1a Department of Internal Medicine , Ronald Reagan UCLA Medical Center , Los Angeles , CA , USA.
Insights
High-intensity statin use in hospitalized high-risk cardiovascular patients is low and varies by medical specialty. Cardiology specialists prescribed high-intensity statins most frequently, highlighting opportunities for quality improvement interventions.
Area of Science:
- Cardiology
- Clinical Pharmacy
- Healthcare Quality Improvement
Background:
- Clinician adherence to 2013 cholesterol-lowering guidelines is inconsistent.
- Understanding statin prescribing patterns among specialists treating high-risk cardiovascular patients is crucial.
Purpose of the Study:
- To examine and compare statin prescribing patterns across different medical specialties.
- To evaluate the utilization of high-intensity statins in high-risk cardiovascular patients post-guideline release.
Main Methods:
- Retrospective chart review of 632 adult patients across Cardiology, CV Surgery, Neurology, and Internal Medicine.
- Analysis of high-intensity statin (atorvastatin 40-80mg, rosuvastatin 20-40mg) prescribing at 6 and 18 months post-2013 guidelines.
- Inclusion criteria: acute coronary syndrome, post-cardiac surgery, carotid procedures, stroke, TIA, or high-risk chest pain.
Main Results:
- Overall high-intensity statin discharge rates were: Cardiology (80%-85%), CV Surgery (52%-65%), Neurology (59%-66%), and Internal Medicine (45%-48%).
- Cardiology demonstrated significantly higher high-intensity statin use compared to other specialties (p < 0.001).
- Cardiology, CV Surgery, and Neurology showed significant increases in high-intensity statin use from admission to discharge.
Conclusions:
- High-intensity statin therapy is underutilized in hospitalized high-risk cardiovascular patients.
- Significant variations in statin prescribing exist among different medical specialties.
- Findings support the development of quality improvement interventions to enhance statin utilization in this population.
Objectives:
Clinician utilization of the 2013 cholesterol lowering guidelines remains variable and unknown. We sought to examine statin prescribing patterns and compare rates among specialists who treat high-risk cardiovascular patients admitted to the hospital.
Methods:
We retrospectively (via chart review) examined four specialty groups: (i) Cardiology, (ii) Cardiovascular or Vascular (CV) Surgery, (iii) Neurology, and (iv) Internal Medicine. Adult patients were included based on a discharge diagnosis of acute coronary syndrome, coronary artery bypass graft surgery, carotid endarterectomy, acute ischemic stroke, transient ischemic attack, or high-risk chest pain. Prescribing patterns were evaluated 6 months and 18 months after the release of the 2013 guidelines. High-intensity statin was defined as atorvastatin 40-80 mg or rosuvastatin 20-40 mg per day.
Results:
632 patients were included in our study. The following percentages of patients were discharged on high-intensity statin (6 months; 18 months): (i) Cardiology (80%; 85%), (ii) CV Surgery (52%, 65%), (iii) Neurology (59%; 66%), and (iv) Internal Medicine (45%; 48%). Among the four groups, Cardiology was the most likely to discharge patients on high-intensity statin (p < 0.001) in 2014 and in 2015. Cardiology, CV Surgery, and Neurology significantly increased the percentage of patients on high-intensity statin from pre-admission to time of discharge in both years.
Conclusion:
High-intensity statin therapy is underutilized among high-risk cardiovascular patients admitted to the hospital. Variations exist in prescribing patterns of different specialties who manage high-risk populations. This data can be used to test quality improvement interventions to improve rates of high-intensity statin utilization among high-risk patients prior to hospital discharge.
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