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Updated: Mar 8, 2026

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
Published on: August 9, 2024
Current Status of Ventilation-Perfusion Scintigraphy for Suspected Pulmonary Embolism
Darlene Metter1, Mark Tulchinsky2, Leonard M Freeman3
11 Department of Radiology, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229.
Objective:
The purpose of this article is to outline recent progress made in ventilation-perfusion (V/Q) scintigraphy imaging techniques and the interpretation systems used for the diagnosis of pulmonary embolism (PE). Various state-of-the-art approaches that can be selected according to the needs dictated by the medical practice environment and specific patient groups are presented.
Conclusion:
Although advances in tomographic imaging have certainly improved the sensitivity of V/Q scans for the diagnosis of PE, they may lead to overdiagnosis by revealing small and clinically insignificant PEs.
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