Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities

Area of Science:

• Oncology
• Molecular Biology
• Radiology

Background:

• Oncology is rapidly evolving towards personalized cancer treatment.
• Targeted therapies focusing on molecular features and the tumor microenvironment are increasingly common.
• Understanding treatment response and toxicity is crucial for effective patient management.

Purpose of the Study:

• To review anti-angiogenic and molecular targeted therapies in oncology.
• To focus on typical and atypical response patterns to these therapies.
• To discuss imaging manifestations of drug-induced toxicities.

Main Methods:

• Literature review of anti-angiogenic and molecular targeted therapies.
• Analysis of response patterns in cancer patients.
• Review of imaging findings related to drug toxicities.

Main Results:

• Discussion of various molecular targeted agents and their mechanisms.
• Identification of characteristic and unusual treatment response patterns.
• Correlation of specific imaging findings with known drug toxicities.

Conclusions:

• Molecular targeted therapies represent a significant advancement in cancer care.
• Accurate interpretation of imaging is essential for assessing treatment efficacy and managing adverse events.
• Further research is needed to optimize the use of targeted therapies and their monitoring.