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Development of actinobacterial resources for functional cosmetics.
Ram Hari Dahal1, Dong Seop Shim2, Jaisoo Kim1
1Department of Life Science, College of Natural Sciences, Kyonggi University, Suwon, Gyeonggi-Do, South Korea.
Journal of Cosmetic Dermatology
|January 19, 2017
Summary
Actinobacteria isolated from soil exhibit potent antibacterial and enzyme inhibitory properties. These findings highlight their potential for developing novel cosmetic ingredients targeting skin health and aging.
Area of Science:
- Microbiology
- Biotechnology
- Cosmetic Science
Background:
- Actinobacteria are known producers of diverse bioactive compounds.
- Exploring microbial resources is crucial for discovering novel functional ingredients.
Purpose of the Study:
- To isolate and identify soil actinobacteria with antibacterial and enzyme inhibitory activities.
- To assess their potential for cosmetic applications.
Main Methods:
- Isolation of soil bacteria.
- Screening for antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis.
- Assaying for tyrosinase, elastase inhibition, and free radical scavenging activity.
Main Results:
- Twelve actinobacterial strains showed antibacterial activity against P. acnes and S. epidermidis.
- Selected strains demonstrated significant tyrosinase and elastase inhibition, comparable to standards.
- Two strains exhibited potent DPPH radical scavenging activity.
Conclusions:
- The isolated actinobacteria possess valuable antibacterial and enzyme inhibitory properties.
- These strains are promising candidates for the development of active cosmetic ingredients.
- Further research can focus on metabolite production for cosmetic formulations.
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