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Updated: Mar 8, 2026
Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
Published on: March 21, 2025
Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid
P A T Martins1, S Alsaiari1, K Julfakyan1
1Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia. niveen.khashab@kaust.edu.sa.
Abstract:
We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.
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