Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is there a SERM in your menopause toolkit?

James H Liu1

  • 1Case Western Reserve University School of Medicine, Cleveland, OH.

Menopause (New York, N.Y.)
|January 19, 2017
PubMed
Summary

Selective estrogen receptor modulators (SERMs) offer tissue-specific estrogen effects, acting as antagonists or agonists. This pearl reviews SERMs for managing menopausal symptoms in clinical practice.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel negative pressure treatment for the genitourinary syndrome of menopause: a feasibility pilot study with the VITA AV clinical system.

Menopause (New York, N.Y.)·2026
Same author

A transdisciplinary approach to growing an applied science of cultural evolution for a sustainable future.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same author

Role of progestogens in hormone therapy.

Menopause (New York, N.Y.)·2025
Same author

Between east and west, between past and future: The effects of exclusive historical victimhood on geopolitical attitudes in Hungary and Serbia.

The British journal of social psychology·2024
Same author

Multimorbidity in postmenopausal women: a new health challenge.

Menopause (New York, N.Y.)·2024
Same author

Behavioral evidence for global consciousness transcending national parochialism.

Scientific reports·2023

Area of Science:

  • Endocrinology
  • Pharmacology

Background:

  • Selective estrogen receptor modulators (SERMs) have been developed over the last 30 years.
  • SERMs can act as estrogen receptor antagonists or agonists depending on the tissue.
  • These compounds modulate estrogen receptor activity.

Purpose of the Study:

  • To provide a clinical overview of SERMs for menopausal patients.
  • To highlight SERMs as a therapeutic option for clinicians.

Main Methods:

  • Review of existing literature on SERMs.
  • Focus on clinical applications in menopausal management.

Main Results:

  • SERMs provide a versatile approach to hormone modulation.
  • Clinicians can utilize SERMs to target specific estrogenic effects.

Conclusions:

  • SERMs represent an important class of drugs for menopausal care.
  • Understanding SERM tissue-specific actions is key for effective patient management.

Related Experiment Videos