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Updated: Mar 8, 2026
A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
Source of Ectopic ACTH Secretion Easily Identified by 68 Ga DOTANOC PET/CT
Sofiullah Abubakar1, Yaw Ampem Amoako, Tessa Kotze
1From the Nuclear Medicine Division, Groote Schuur Hospital/University of Cape Town, Cape Town, South Africa.
Abstract:
Malignant tumors account for most sources of ectopic ACTH Cushing syndrome (EA-CS). Early localization of the source and complete removal can be curative and also prevent metastasis. Diagnostic CT is known to perform better than PET/CT (low dose) in characterizing lung pathologies. However, bronchial carcinoids, a common source of EA-CS, may be difficult to detect on chest CT scan especially when it is small and located close to the hilar region. We present a case of EA-CS due to bronchial carcinoid, which was easily seen on Ga DOTANOC PET/CT after a diagnostic chest CT was reported as normal.
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