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Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspects
Flávio Ramalho Romero1, Gabriela Roncada Haddad1, Hélio Amante Miot1
1Universidade Estadual Paulista "Júlio de Mesquita Filho" (Unesp) - Botucatu (SP), Brazil.
Palmar hyperhidrosis, excessive sweating of the hands, significantly impacts quality of life. This review covers its causes, diagnosis, and treatment options, including surgical interventions.
Area of Science:
- Medicine
- Physiology
- Surgery
Background:
- Palmar hyperhidrosis affects up to 3% of the population, causing excessive hand sweating unrelated to thermoregulation.
- This condition stems from localized hyperactivity within the sympathetic autonomic nervous system.
- Stressful events can trigger or exacerbate symptoms of palmar hyperhidrosis.
Purpose of the Study:
- To provide a comprehensive overview of palmar hyperhidrosis.
- To discuss the clinical presentation, pathophysiology, and diagnostic methods.
- To review current therapeutic strategies, encompassing both clinical and surgical approaches.
Main Methods:
- Literature review of clinical findings, pathophysiology, diagnostics, and therapeutics for palmar hyperhidrosis.
- Synthesis of information on the sympathetic autonomic nervous system's role.
- Analysis of established and emerging treatment modalities.
Main Results:
- Palmar hyperhidrosis is a distinct clinical entity with identifiable pathophysiological underpinnings.
- Diagnostic criteria focus on clinical presentation and exclusion of secondary causes.
- A range of treatments exist, from conservative management to surgical sympathectomy.
Conclusions:
- Effective management of palmar hyperhidrosis requires understanding its multifactorial nature.
- Both medical and surgical treatments offer viable options for patients.
- Further research can refine diagnostic accuracy and therapeutic outcomes for this quality-of-life impacting condition.
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