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Published on: September 26, 2016
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Bacillary angiomatosis with bone invasion.
Lucia Martins Diniz1, Karina Bittencourt Medeiros1, Luana Gomes Landeiro1
1Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
Anais Brasileiros De Dermatologia
|January 19, 2017
Summary
Bacillary angiomatosis, an infection by Bartonella henselae and B. quintana, was diagnosed in an advanced AIDS patient. The case highlights skin and bone lesions caused by this rare opportunistic infection in severely immunocompromised individuals.
Area of Science:
- Infectious Diseases
- Dermatology
- Immunology
Background:
- Bacillary angiomatosis is a vascular proliferation caused by Bartonella henselae or B. quintana.
- It is a rare opportunistic infection predominantly seen in patients with advanced acquired immunodeficiency syndrome (AIDS).
Observation:
- A case report of a 29-year-old male with AIDS and a CD4+ cell count of 9/mm³ is presented.
- The patient exhibited disseminated reddish-violet papular and nodular skin lesions, particularly on the hand and finger.
- Radiography revealed osteolysis of the distal phalanx.
Findings:
- Histopathological examination of skin and bone lesions showed vascular proliferation consistent with bacillary angiomatosis.
- The presence of bacilli confirmed the diagnosis.
- The case aligns with literature describing this infection in severely immunocompromised young adults.
Implications:
- This case underscores the importance of considering bacillary angiomatosis in the differential diagnosis of skin and bone lesions in patients with advanced immunosuppression.
- Early diagnosis and treatment are crucial for managing this opportunistic infection.
- Further research into the pathogenesis and treatment of bacillary angiomatosis in immunocompromised populations is warranted.
