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Related Concept Videos

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Related Experiment Video

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Technical Note: Fast respiratory motion estimation using sorted singles without unlist processing: A feasibility

Jaewon Yang1, Mehdi Khalighi2, Thomas A Hope1,3

  • 1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.

Medical Physics
|January 19, 2017
PubMed
Summary
This summary is machine-generated.

Fast respiratory motion estimation is feasible using positron emission tomography (PET) singles data in PET/MRI scans. This singles-driven respiratory motion (SDRM) method offers rapid processing for potential use in gated PET imaging.

Keywords:
PET/MRIdata-driven gatingrespiratory motionsingles

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Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Biophysics

Background:

  • Respiratory motion significantly impacts PET image quality and quantification.
  • Current gating methods can be complex or require external equipment.
  • Efficient motion estimation is crucial for accurate PET/MRI studies.

Purpose of the Study:

  • To demonstrate the feasibility of fast respiratory motion estimation using PET singles data.
  • To validate a novel singles-driven respiratory motion (SDRM) method.
  • To assess SDRM's potential for data-driven gating (DDG) in PET/MRI.

Main Methods:

  • PET list-mode data from SIGNA PET/MR systems were utilized.
  • Singles data were recorded and binned per second for each detector crystal.
  • Singles-driven respiratory motion (SDRM) traces were derived by summing detector singles.
  • SDRM traces were compared to bellows (pressure belt) traces in five liver-focused 68 Ga-DOTA-TOC PET/MRI scans.
  • Quantitative evaluation included Pearson's correlation and trigger time differences.

Main Results:

  • The SDRM trace derivation averaged 4.2 ± 0.42 seconds.
  • Reading singles data constituted the majority of the processing time (3.1 ± 0.40 seconds).
  • Average correlation between SDRM and bellows traces was 0.69 ± 0.16.
  • Average time offset of SDRM triggers was 0.25 ± 0.39 seconds relative to bellows triggers.

Conclusions:

  • PET singles-driven respiratory motion (SDRM) estimation is feasible using readily available list-mode data.
  • The SDRM method demonstrates potential for rapid, data-driven gating in PET imaging.
  • This proof-of-principle study highlights SDRM's efficiency for motion-compensated PET/MRI.