Search research articles

Related Concept Videos

Auditory Pathway

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...

Auditory Perception

Auditory Perception

The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...

Hearing

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

Perceiving Loudness, Pitch, and Location

Perceiving Loudness, Pitch, and Location

The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating the Association Between Patient Priorities and ICU Care Delivery in Adults Receiving Mechanical Ventilation.

Chest·2026

Same author

Impact of a web-based breast cancer surgery decision aid on knowledge and perceptions of feeling informed in clinics that care for socioeconomically disadvantaged patients: An Alliance Clinical Trial (A231701CD).

Cancer·2026

Same author

Bayesian Model Calibration and Sensitivity Analysis for Oscillating Biological Experiments.

Technometrics : a journal of statistics for the physical, chemical, and engineering sciences·2025

Same author

Optimising time-limited trials in acute respiratory failure: a multicentre focused ethnography protocol.

BMJ open·2025

Same author

Evaluating the economic impact of bariatric surgery: A multi-year comparative analysis.

American journal of surgery·2025

Same author

Impact of a Web-Based Decision Aid on Socioeconomically Disadvantaged Patients' Engagement in Breast Surgery Decision-Making: Stepped-Wedge Clinical Trial (Alliance-A231701CD).

Annals of surgical oncology·2025

Same journal

Fast penalized generalized estimating equations for large longitudinal functional datasets.

Biometrics·2026

Same journal

Causally-interpretable random-effects meta-analysis.

Biometrics·2026

Same journal

Statistical inference for mean function of partially observed functional time series.

Biometrics·2026

Same journal

Subgroup identification via Interaction Tree and Mixed Model for Repeated Measures with application to Alzheimer's disease.

Biometrics·2026

Same journal

Finite mixtures of linear quantile regressions with concomitant variables: a solution to endogeneity in longitudinal data modeling.

Biometrics·2026

Same journal

Discussion on "INTACT: a method for integration of longitudinal physical activity data from multiple sources" by Jingru Zhang, Erjia Cui, Hongzhe Li, and Haochang Shou.

Biometrics·2026

See all related articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Mar 8, 2026

Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Estimation and testing problems in auditory neuroscience via clustering.

Youngdeok Hwang¹, Samantha Wright², Bret M Hanlon³

¹Department of Statistics, Sungkyunkwan University, 03063 Seoul, Korea.

|January 19, 2017

Summary

This summary is machine-generated.

This study introduces a new statistical method to accurately estimate the number of neural response clusters in auditory processing experiments. This technique improves the analysis of synaptic currents, overcoming limitations posed by biological variability.

Keywords:

Electrophysiology Gaussian mixture Singular value decomposition Synaptic current

More Related Videos

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

Optogenetic Stimulation of the Auditory Nerve

Optogenetic Stimulation of the Auditory Nerve

Published on: October 8, 2014

Related Experiment Videos

Last Updated: Mar 8, 2026

Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

Optogenetic Stimulation of the Auditory Nerve

Optogenetic Stimulation of the Auditory Nerve

Published on: October 8, 2014

Area of Science:

Neuroscience
Computational Neuroscience
Statistical Analysis

Background:

Auditory information processing in neurons is crucial for understanding the auditory system.
Electrophysiological experiments record synaptic current responses, often appearing as clusters.
Visual estimation of cluster number is challenging due to biological variability blurring distinct groups.

Purpose of the Study:

To develop a robust statistical method for estimating the number of clusters in synaptic current responses.
To provide tools for hypothesis testing and sample size determination in two-sample electrophysiological studies.
To address the challenge of quantifying neural response characteristics obscured by biological noise.

Main Methods:

Singular value decomposition (SVD) for dimensionality reduction and pattern identification.
Gaussian mixture modeling (GMM) for probabilistic clustering of neural data.
Statistical hypothesis testing and sample size calculations for comparative analyses.

Main Results:

A novel estimator for the number of clusters was developed using SVD and GMM.
The proposed methods were validated using both simulated and real experimental electrophysiological data.
The approach effectively quantifies a key characteristic of the auditory system that is difficult to assess visually.

Conclusions:

The developed statistical framework accurately estimates neural response clusters in auditory processing.
This method enhances the analysis of electrophysiological data, offering improved insights into neural function.
The study provides valuable tools for future research in auditory neuroscience and related fields.