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Related Experiment Videos

Processed Aloe vera administered topically inhibits inflammation.

R H Davis, K Y Rosenthal, L R Cesario

    Journal of the American Podiatric Medical Association
    |August 1, 1989
    PubMed
    Summary
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    Topical Aloe vera preparations effectively reduce skin inflammation. Decolorized Aloe vera showed greater anti-inflammatory effects than colorized versions in a croton oil-induced edema assay.

    Area of Science:

    • Dermatology
    • Pharmacology
    • Botany

    Background:

    • Inflammation is a common skin condition.
    • Aloe vera is a plant with a history of medicinal use.
    • Understanding the anti-inflammatory properties of Aloe vera is important.

    Purpose of the Study:

    • To evaluate the topical anti-inflammatory activity of Aloe vera preparations.
    • To compare the efficacy of decolorized versus colorized Aloe vera.
    • To establish a baseline for assessing Aloe vera's biological activity in treating inflammation.

    Main Methods:

    • Croton oil-induced edema assay was used to test anti-inflammatory activity.
    • Aloe vera preparations (decolorized and colorized) were applied topically.
    • Inhibition of inflammation was measured.

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    Main Results:

    • Topical application of small amounts of Aloe vera inhibited inflammation.
    • Decolorized Aloe vera was generally more effective than colorized Aloe vera.
    • A 5% concentration of decolorized irradiated Aloe vera achieved 47.1% inflammation inhibition.

    Conclusions:

    • Aloe vera exhibits significant topical anti-inflammatory activity.
    • Decolorized Aloe vera may be more potent for treating inflammation.
    • Results provide a baseline for podiatric physicians using Aloe vera for inflammatory conditions.