Janus PEGylated gold nanoparticles: a robust colorimetric probe for sensing nitrite ions in complex samples
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Updated: Mar 8, 2026

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
Published on: December 25, 2016
Yanmei Xiong1, Mingmin Li1, Huiqiao Liu1
1State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, and Tianjin Key Laboratory of Molecular Recognition and Biosensing, College of Chemistry, Nankai University, Tianjin 300071, China. yangjie035@nankai.edu.cn liudb@nankai.edu.cn.
Abstract:
We presented a Janus PEGylated AuNP probe where PEGs and recognition ligands (e.g., 4-aminobenzenethiol, 4-ABT) were asymmetrically functionalized on an AuNP. With this design, the probes showed high colloidal stability, signal robustness, specificity, and sufficient sensitivity in the determination of NO2- in various complex samples.

